Life never goes the way we plan, it never means that we should stop planning.
Rather we must learn to Accept the changes, Admire the U-turns and Be Grateful for the Diversions in our journey.
They emphasize don't say Yes when you want to say NO.
I believe start saying YES even if your logical side says NO. Allow yourself to come out of your comfort zone, embrace the unknown with all it's pros and cons, start exploring new avenues and soon you'll find a New YOU!